Peyronie’s disease is a condition where scar tissue (plaque) develops inside the penis, causing curvature, shortening, and sometimes painful erections. While mild cases can be managed with non-surgical therapies, severe cases may require surgery.
For men in Bangkok, both non-surgical and surgical options are available at specialized men’s health clinics. This article compares both approaches so you can understand which treatment may be right for you.
Non-Surgical Treatments for Peyronie’s Disease
Non-surgical treatments are usually recommended for mild to moderate Peyronie’s or during the early (acute) phase of the condition.
1. Medication and Injections
Collagenase (Xiaflex): FDA-approved injectable that breaks down scar tissue
Verapamil or Interferon injections: Reduce plaque buildup and improve curvature
Oral medications (limited evidence): Vitamin E, pentoxifylline, and others
2. PRP (Platelet-Rich Plasma) Therapy
Uses growth factors from your blood to promote tissue healing
May improve penile elasticity and reduce pain
3. Exosome Therapy
Cell-derived vesicles that signal tissue repair
Potential for reducing scar tissue and improving vascular health
4. Shockwave Therapy (Li-ESWT)
Low-intensity acoustic waves applied to the penis
May soften plaque and improve blood flow
Also improves erectile function in men with ED
Benefits of Non-Surgical Treatments
Non-invasive or minimally invasive
Outpatient procedures, little to no downtime
Best for early-stage Peyronie’s disease
May improve curvature, pain, and erectile function
Limitations:
Results vary between patients
May not fully correct severe curvature
Require multiple sessions or ongoing treatments
Surgical Treatments for Peyronie’s Disease
Surgery is usually recommended when:
Curvature is severe (more than 60–70°)
Sex is painful or impossible
ED does not respond to medication or non-surgical therapy
Main Surgical Options
Plication Surgery
Shortens the longer side of the penis
Straightens mild to moderate curvature
Quick recovery, but may reduce length slightly
Plaque Incision/Excision with Grafting
Scar tissue is cut or removed
A graft is placed to restore penile length and straighten curvature
Best for more severe deformities
Penile Implant (e.g., Titan Coloplast)
Corrects both Peyronie’s curvature and erectile dysfunction
High success rates for men with severe disease
Benefits of Surgery
Permanent correction of severe curvature
Restores ability to have normal sexual intercourse
High patient satisfaction rates (80–90%)
Implant option also treats erectile dysfunction
Limitations:
Invasive procedure requiring anesthesia
Recovery period of 6–8 weeks
Risk of shortening (plication) or ED (after grafting)
Peyronie’s Disease: Surgery vs Non-Surgical Comparison
Aspect | Non-Surgical | Surgical |
Best For | Mild to moderate Peyronie’s, early phase | Severe Peyronie’s, major curvature |
Approach | Injections, PRP, Exosomes, Shockwave | Plication, grafting, or penile implant |
Effectiveness | Varies, may reduce curvature by 20–40% | 80–95% success in full correction |
Recovery Time | Days to weeks | 6–8 weeks |
Invasiveness | Non-invasive/minimally invasive | Invasive (surgery under anesthesia) |
Duration of Results | Temporary or moderate improvement | Permanent (implants can last 10–15 years) |
Which Treatment Is Right for You?
Choose non-surgical options if you:
Are in the early stage of Peyronie’s
Have mild to moderate curvature
Want a non-invasive approach first
Choose surgery if you:
Have severe curvature interfering with sex
Do not respond to medications or PRP/Shockwave
Want a permanent, reliable correction
Many men in Bangkok start with non-surgical options before moving to surgery if needed.
Why Bangkok?
Expert men’s health clinics like Menscape with both surgical and non-surgical options
Lower costs than in the US or Europe
Specialized doctors in urology and regenerative medicine
Confidential care tailored for international and local patients
Frequently Asked Questions (FAQ)
1. Can Peyronie’s disease be cured without surgery?
Mild cases may improve with non-surgical treatments, but severe cases usually require surgery.
2. How do I know if I need surgery?
If curvature is severe, painful, or prevents sex, surgery is often recommended.
3. Are non-surgical treatments effective?
They may improve curvature by 20–40%, especially in early stages.
4. How long does surgical recovery take?
About 6–8 weeks before resuming sexual activity.
5. Which is more affordable in Bangkok?
Non-surgical options are cheaper initially, but surgery provides permanent results.
Key Takeaways
Peyronie’s disease has both surgical and non-surgical treatments available in Bangkok.
Non-surgical therapies (PRP, Exosomes, Shockwave, injections) work best for mild to moderate cases.
Surgical options (plication, grafting, implants) are best for severe cases.
Bangkok offers affordable, expert care for both approaches.
At Menscape, men receive personalized treatment plans tailored to their condition.
Suffering from Peyronie’s disease? Book a confidential consultation at Menscape Bangkok to explore both surgical and non-surgical solutions.

